Feb 5, 2014 · Founded in 1964, the American Society of Clinical Oncology, Inc. (ASCO®) is committed to making a world of difference in cancer care. Through research, education, and promotion of the highest-quality, equitable patient care, ASCO works to conquer cancer and create a world where cancer is prevented or cured, and every survivor is healthy.

Feb 20, 2018 · Neutropenia, a decrease in the absolute neutrophil count (ANC), occurs frequently in recipients of chemotherapy. 1 Neutrophils are critical in providing host defense against infection, particularly bacterial and fungal infections. The risk of infection increases with the depth and duration of neutropenia, with the greatest risk occurring in …

Feb 3, 2020 · As well described in the clinical review by Brown and Gupta 1 in this issue of JCO Oncology Practice, oral mucositis is a common toxicity of cancer therapy.The morbidity of oral mucositis includes pain, nutritional compromise, and infection risk, which potentially result in breaks or dose reductions in cancer therapy.

May 15, 2024 · Brain metastases (BMs) occur in 20%-40% of patients with breast cancer during the course of their disease. 1 BMs from solid tumors contribute significantly to morbidity and/or mortality, with about 200,000 patients—10% of all patients with cancer—diagnosed each year in the United States. 2 Notably, Breast Cancer BMs (BCBM) represents second most common (30%) among all cancers. 3 With ...

Sep 15, 2020 · Significant prognostic factors varied by diagnosis and new prognostic factors were identified. Those factors were incorporated into the updated GPA with robust separation (P < .01) between subgroups.Survival has improved, but varies widely by GPA for patients with non–small-cell lung, breast, melanoma, GI, and renal cancer with brain metastases from 7-47 months, 3-36 months, 5-34 months, 3 ...

In the United States, the Controlled Substance Act renders cannabis with >0.3% delta-9-tetrahydrocannabinol (THC) schedule I. This status signifies that cannabis has no accepted medical use and a high potential for abuse. 20 The schedule I designation creates frequent conflicts between federal and state laws, as 38 states now allow medical cannabis use by adults with qualifying conditions.

Jan 10, 2024 · Clinicians should recommend treatment according to menopausal status, pathological and biomarker features when quality results are available. In first-line, for hormone receptor (HR)–positive MBC, when a non-steroidal aromatase inhibitor and CDK 4/6 inhibitor combination is unavailable, use hormonal therapy alone.

In the United States, it is estimated that between 8% and 10% of patients with cancer will develop brain metastases representing approximately 200,000 new patients with brain metastases every year. 1 The point prevalence of brain metastases on initial diagnosis varies widely between different cancer histologies. For example, the incidence proportion of patients with metastatic cancer who have ...

Immunotherapy has revolutionized the treatment of many different types of cancers. Immune checkpoint inhibitors (ICPis) targeting cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4), programmed cell death-1 (PD-1), and PD ligand 1 (PD-L1) work by preventing the receptors and ligands from binding to each other, thereby disrupting signaling so that T cells can recognize and attack cancer ...

May 15, 2024 · Evidence-based recommendations address the integration of palliative care in oncology. Oncology clinicians should refer patients with advanced solid tumors and hematologic malignancies to specialized interdisciplinary palliative care teams that provide outpatient and inpatient care beginning early in the course of the disease, …