Identification of a nitric oxide-regulated transitional state of Müller glia reveals a key mechanism enabling neuronal regeneration in the injured vertebrate retina.

High-profile news coverage that eLife papers generated in October 2025, including NPR, One Earth and Neuroscience News.

The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse ...

Researchers have mapped the cellular diversity of the eye’s fluid drainage tissue, uncovering a cell subtype that may contribute to glaucoma progression and respond to vitamin B3 treatment.

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a ...

Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

An agreement between universities, research institutes and funders to support the career development of researchers in the UK has led to improvements in research culture since 2019, but there is still ...

Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular ...

The glial-specific role of betaPix during cerebral blood vessel development has been revealed by establishing a new betaPix conditional trap allele in zebrafish.