Longevity India Conference 2025 Concludes, Highlighting Policy, Elder Care, and Public Health Perspectives
The Longevity India Conference 2025 - Rise for Healthy Aging, hosted at the Indian Institute of Science (IISc), concluded its final day with impactful discussions on longevity science. The discussions ...
GEN - Genetic Engineering and Biotechnology News12d
Emerging Approaches for Targeted Protein Degradation
Successful research in targeted protein degradation depends not only on measurements at high sensitivity, speed and precision ...
Pharmaceutical Technology13d
Why pharma is still far from a treatment for galactosemia
With issues in therapy delivery and a barren trial landscape, short-term chances for a commercial galactosemia treatment are ...
C&EN14d
Design, Synthesis, and Biological Evaluation of Marchantin C-NO Donor Hybrids for Overcoming Pgp-Mediated Drug Resistance by Targeting Lysosome
Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, Shandong University, Jinan 250012, P. R. China ...
C&EN18d
Lysosome-Specific Delivery of β-Glucosidase Enzyme Using Protein-Glycopolypeptide Conjugate via Protein Engineering and Bioconjugation
Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, Nadia, West Bengal 741246, India ...
PNAS27d
Correction for Wu et al., Hapalindole Q suppresses autophagosome−lysosome fusion by promoting YAP1 degradation via chaperon-mediated autophagy
The title should instead appear as “Hapalindole Q suppresses autophagosome−lysosome fusion by promoting YAP1 degradation via chaperone-mediated autophagy.” The legends for Figs. 1, 5, and 6 appeared ...
PNAS27d
Correction for Schmidt et al., Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2
The authors note that Constanza Torres-Paris should be added to the author list between Steve Silletti and Junru Hu. Constanza Torres-Paris should be credited with designing research, performing ...
Phys.org29d
Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomes
Fats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...
Science Daily1mon
Inability of cells to recycle fats can spell disease
Once fats are broken down in the lysosome, they serve several important roles in the cell. One is membrane repair and maintenance. The broken-down fat components, such as phospholipids and ...
EurekAlert!1mon
NUS Medicine study: Inability of cells to recycle fats can spell disease
Once fats are broken down in the lysosome, they serve several important roles in the cell. One is membrane repair and maintenance. The broken-down fat components, such as phospholipids and ...