McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

A year ago it was either Brandon Allen or Joshua Dobbs behind Purdy, and it didn’t turn out well for the 49ers.

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

The last time we heard from San Francisco 49ers head coach Kyle Shanahan was on Thursday, when he still hadn’t decided ...

The San Francisco 49ers added some running back depth to their roster ahead of their preseason opener vs. the Denver Broncos.

The Denver Broncos and the San Francisco 49ers will kick off their 2025 preseason at Levi's Stadium on Saturday.

Ahead of the Denver Broncos ' preseason game against the San Francisco 49ers tonight, we asked Kyle Madson of Niners Wire ...

The San Francisco 49ers entered Saturday's game with just four running backs, and they lost one of them in the third quarter.

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled in a 30-9 loss against the ...

The 49ers won't play their starters in their preseason debut against the Denver Broncos, but these 11 players will be worth ...

The San Francisco 49ers signed running back Ke’Shawn Vaughn to a one-year deal ahead of their first preseason game against the Denver Broncos. Vaughn signed with the 49ers’ practice squad in August ...

Kittle isn't warming up ahead of Saturday's preseason game against the Broncos and isn't slated to play, Nick Wagoner of ESPN.com reports.