The SportsLine Projection Model has revealed its Houston Cougars vs. Duke Blue Devils picks for the Final Four of the 2025 NCAA Tournament on Saturday

The No. 2 seed Huskies are back in the Final Four for the 24th time as Paige Bueckers scores 31 and and Sarah Strong puts up 22 points and 17 rebounds to lead the way. USC put up an impressive showing despite missing star JuJu Watkins to a season-ending injury, but the Trojans didn't have the firepower to keep up.