Mykel Williams wasn't the only rookie draft pick who was injured this week. Running back Jordan James did not participate in ...

San Francisco 49ers running back Jordan James did not suit up for the 49ers joint practice with the Denver Broncos. The ...

The San Francisco 49ers preseason slate opens Saturday evening against the Denver Broncos at Levi's Stadium.

A rookie running back has an especially big target, but Jordan James held up just fine. The San Francisco 49ers lost talented ...

The San Francisco 49ers had two injury scares in Thursday's joint practice with the Denver Broncos, but it sounds like the ...

San Francisco 49ers coach Kyle Shanahan announced that rookie running back Jordan James suffered a broken finger and will be "out a couple of weeks." ...

San Francisco head coach Kyle Shanahan said Thursday that James will miss a couple weeks due to a broken finger, Cam Inman of The San Jose Mercury News reports. James will require surgery to address ...

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled by halftime against the ...

The San Francisco 49ers entered Saturday's game with just four running backs, and they lost one of them in the third quarter.

No team has suffered more injuries to the running back position than the San Francisco 49ers in recent years. Rookie RB Jordan James is the latest to suffer a serious injury in the San Francisco backf ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Taylor rushed five times for seven yards and a touchdown and secured his only target for four yards in the 49ers ' 30-9 preseason loss to the Broncos on Saturday night.