The Longevity India Conference 2025 - Rise for Healthy Aging, hosted at the Indian Institute of Science (IISc), concluded its final day with impactful discussions on longevity science. The discussions ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

TEDC1 and TEDC2, functions in generating centriolar triplet microtubules, and that this is crucial for the proper formation of centriolar subdomains and the stability of centrioles throughout the cell ...

Successful research in targeted protein degradation depends not only on measurements at high sensitivity, speed and precision ...

With issues in therapy delivery and a barren trial landscape, short-term chances for a commercial galactosemia treatment are ...

Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, Shandong University, Jinan 250012, P. R. China ...

Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, Nadia, West Bengal 741246, India ...

U.S., and colleagues have designed and constructed a lysosome-targeted photoinduced pyroptosis and ferroptosis theranostic nanoplatform M@P by self-assembly of photosensitizer MTCN-3 and ...

The title should instead appear as “Hapalindole Q suppresses autophagosome−lysosome fusion by promoting YAP1 degradation via chaperone-mediated autophagy.” The legends for Figs. 1, 5, and 6 appeared ...

The authors note that Constanza Torres-Paris should be added to the author list between Steve Silletti and Junru Hu. Constanza Torres-Paris should be credited with designing research, performing ...