Rise for Healthy Aging, hosted at the Indian Institute of Science (IISc), concluded its final day with impactful discussions on longevity science. The discussions emphasized data-driven policy ...

Fats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...

Successful research in targeted protein degradation depends not only on measurements at high sensitivity, speed and precision ...

Lorsque ces cellules immunitaires avalent des bactéries, surtout mortes, elles recyclent une partie de leurs composés pour ...

With issues in therapy delivery and a barren trial landscape, short-term chances for a commercial galactosemia treatment are ...

Elevation Oncology, Inc. a publié ses résultats pour le quatrième trimestre et l'ensemble de l'exercice clos le 31 décembre ...

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

Representatives from four leading companies highlight emerging basic and clinical research that drives renewed optimism.

In a recent Perspective in Nature Immunology 1, Blander and Medzhitov explored the function of Toll-like receptor (TLR) signaling in controlling the maturation of phagosomes in macrophages and ...

Neurodegenerative diseases, including Alzheimer’s and Parkinson’s, are progressive conditions marked by neuronal loss, neuroinflammation, and protein ...

Mechanistically, Mtb Mce3C can bind host cathepsin B (CTSB), a lysosome-derived non-caspase protease that determines cell modalities. This binding inhibits CTSB's protease activity towards BH3 ...