Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kareniacean plastids are distinct from those ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. High fructose intake during pregnancy ...
Transient receptor potential vanilloid 1 (TRPV1) is a capsaicin-sensitive ion channel implicated in pain sensation. While TRPV1 potentiation in hyperalgesia development has been extensively ...
Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics
imageimageCryo-EM analysis of the AC8-Gαs complex in the presence of calmodulin reveals the activated state of AC8. Structural proteomics analysis of AC8 and its interaction partners sheds new light ...
A fundamental tenet of the scientific process is that science is self‐correcting. Efficient correction of the scientific literature requires a more nuanced set of policies and tools that lower the bar ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback.
Carbon source-dependent control of bacterial growth is fundamental to bacterial physiology and survival. However, pinpointing the metabolic steps important for cell growth is challenging due to the ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Fate determination of primordial germ cells ...
Multiple initiatives have attempted to define and recommend the annotation of images with metadata. However, proper documentation of complex and evolving projects is a difficult task, and the variety ...
Reversal of tumor-induced natural killer (NK) cell dysfunction remains a major hurdle to overcome for the clinical success of immunotherapies based on NK cells targeting solid tumors. New research in ...
There is a growing trend for directing research funding in the life sciences toward “mission‐driven” projects. This can involve high‐profile initiatives, often generously supported by philanthropic ...
Most senior scientists who have carved out a career in science eventually look back at how they managed to get there. Many may feel that their position is a just reward for their hard work and ...
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