Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease, both ...
Insulin orchestrates systemic glucose homoeostasis by engaging a cell-surface tyrosine kinase receptor and activating a network of intracellular pathways. Upon insulin binding, the insulin receptor ...
Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...
Insulin metabolism encompasses the synthesis of proinsulin in pancreatic β-cells, its processing into mature hormone and C-peptide, and regulated release in response to glucose and incretin signals.
Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity. The insulin superfamily of hormones, ...
Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...
Insulin-producing β-islet cells in the pancreas can be made aware of a lack of insulin in the blood in a diabetes model, through signals relayed by a soluble signaling molecule called T-cadherin, ...
Youths who start using an automated insulin delivery system within 6 months of type 1 diabetes diagnosis are 82% more likely ...
Study identifies a specific link between insulin resistance, brain structure, and cognitive impairment in Bipolar Disorder, ...
Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include stimulation ...
A new study focuses on the insulin receptor to understand its role in the development of type 2 diabetes mellitus, a metabolic disease with a major impact on global health. Insulin resistance precedes ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results