A small, pilot study testing prasugrel without aspirin after PCI in low-risk patients with stable coronary artery disease suggests monotherapy with the P2Y12 inhibitor is feasible and safe, with ...

When dual antiplatelet therapy was stopped 12 months after PCI, clopidogrel monotherapy lowered cardiovascular and bleeding ...

Dual antiplatelet therapy after heart bypass surgery is not more effective than aspirin alone - and it increases the risk of excessive bleeding. This has now been shown in a study of 2,201 patients at ...

Patients benefit from antiplatelet therapy after coronary-artery bypass grafting (CABG) for an acute coronary syndrome. Whether the addition of ticagrelor to aspirin, as compared with aspirin alone, ...

Oral antiplatelet agents such as aspirin and clopidogrel are used to prevent strokes, heart attacks, and other atherothrombotic events. Certain invasive procedures carry a degree of bleeding risk that ...

Dual antiplatelet therapy (DAPT) was not more effective than aspirin alone for the prevention of major adverse cardiovascular events and increased major bleeding in patients with acute coronary ...

Based on an analysis of a decade of hospital stroke registry data, people who had brain bleeds were more likely to die in the hospital if they were taking multiple antiplatelet medications, or ...

Nearly all PCI patients, even those at low risk of bleeding, develop at least some gastrointestinal injury when taking dual antiplatelet therapy (DAPT), according to data from the OPT-PEACE randomized ...

Currently available antiplatelet drugs interfere with certain steps in the activation process by selectively blocking key platelet enzymes or receptors, reducing the risk of arterial thrombosis ...