The identification of the cellular targets of small molecules with anticancer activity is crucial to their further development as drug candidates. Here, we present the application of a large-scale RNA ...
Researchers from the Biogerontology Research Foundation , Department of Molecular Neuroscience at the Swammerdam Institute for Life Sciences at the University of Amsterdam, and the Department of ...
RNA interference is a biological process that has evolved with the evolution of mammals and plays an important role in transient and long-term blocking of protein expression. Short Hairpin RNA (shRNA) ...
To investigate the effects of selective knockdown of TRPV1 channels in the lower thoracic and upper lumbar segments of spinal cord, dorsal root ganglia (DRG) and mesenteric arteries on rat blood ...
RNA-based therapies are enjoying a renaissance, owing in part to the recent approvals of Alnylam Pharmaceuticals’ RNA interference (RNAi) drugs, Onpattro ® (patisiran) and Givlaari™ (givosiran).
A powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi, has been developed by scientists. Scientists at Cold Spring Harbor ...
An increase in serum choline levels to predict progression-free survival (PFS) in patients (pts) with advanced cancers receiving pembrolizumab. A phase I, dose-escalation study of ADG106, a fully ...
Cold Spring Harbor, NY - Scientists at Cold Spring Harbor Laboratory (CSHL) have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA ...
STUART, Fla.--(BUSINESS WIRE)--Cognigenics, a pioneering company in RNA-based therapeutics for neuropsychiatric conditions and neurocognitive disorders, announced the publication of its latest ...
Sigma-Aldrich has announced the release of the MISSION™ TRC shRNA human and mouse libraries for RNA interference-based research. The collection now carries approximately 65,000 shRNA vector constructs ...
Sigma, a division of Sigma-Aldrich Corporation, through an exclusive agreement with The RNAi Consortium (TRC), has announced the expansion of the MISSION TRC shRNA library product lines to include ...
What is Short Hairpin RNA? RNA serves a wide variety of roles within a cell, carrying out catalytic, regulatory, structural and genetic transferal functions. A type of artificial RNA, called short ...
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