Toll-like receptors (TLRs) constitute a critical family of proteins that detect conserved microbial structures, known as pathogen-associated molecular patterns (PAMPs), to rapidly initiate the innate ...

Twas a head-scratcher: Twelve years ago, researchers found that a receptor, known for its role in a fruit fly dorsoventral patterning called Toll, was related to an important mammalian immune receptor ...

On immune cells, Toll-like receptors are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the ...

Researchers from the University of Bonn are using an innovative method to watch immune receptors go about their business. Immune cells are capable of detecting infections just like a sniffer dog, ...

Toll-like receptors, or TLRs, are the immune system’s early warning sensors. They detect microbial invaders and damage signals, helping the body mount a defense. But when TLR signaling veers off ...

Toll-like receptors (TLRs) are vital components of the immune system, acting as sentinels that detect and respond to ...

Many autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 receptors, which recognize the nucleic acids ...

Toll-like receptor (TLR) and saponin adjuvants have each improved vaccine potency and safety. Now, researchers at Stanford University report that combining them in a nanoparticle format improves not ...

Felicitas Lauber (left), Dr. Janine Holze (center) and Professor Günther Weindl (right) used an innovative method to observe immune receptors at work. Immune cells are capable of detecting infections ...