As a fast and easy-to-use gene-editing technique, CRISPR is one of the biggest discoveries in 21 st century medical science, and an important facilitator of gene therapy development. Several gene ...

Researchers introduce Variant-aware Cas-OFFinder, a web-based tool that improves CRISPR off-target predictions by incorporating individual genetic differences. By reconstructing allele-specific ...

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology ...

QurAlis Demonstrates Effects on Disease Progression and Target Engagement in ANQUR Clinical Trial of QRL-201, a First-in-Class Precision Medicine in Development for Sporadic ALS First clinical ...

DeepTarget’s predictions are based on the principle that removing a gene encoding the protein target of a given drug through CRISPR-Cas9 gene editing can mimic the inhibitory effects of that drug. The ...

A team of scientists has identified an enzyme called PurF as a new drug target for tuberculosis, offering a fresh line of attack against a disease that kills more than a million people each year. The ...