Affecting both people and animals, prion diseases are degenerative brain disorders that can debilitate or kill their victims. The most common form of prion disease affecting humans is sporadic ...

The most common cause of inherited prion diseases is the E200K mutation of the prion protein (PrP). It is often thought that this mutation causes disease by making PrP more susceptible to misfolding ...

August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

Canadians originally diagnosed with a mystery brain disease had other, well-known neurologic conditions, cross-sectional data suggested. The study assessed 25 of 222 cases listed in public health ...

Health officials in Hood River County, Ore., are investigating three cases of a rare and fatal brain disease known as Creutzfeldt-Jakob disease. Two people have died and a third person is showing ...

(Boston)—Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of ...