Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...

Subscribe to our newsletter for the latest sci-tech news updates. In the study, published in Nature Cancer, investigators dove deep into the molecular biology of non-small cell lung cancer to pinpoint ...

Acute myeloid leukemia (AML) is a rare and aggressive hematologic malignancy. AML progresses rapidly and is indicated by an excess of immature white blood cells. It is caused by high mutational burden ...

Checkpoint inhibitors are a groundbreaking class of cancer treatment, but they come with two frustrating challenges. In some cases, tumors show no initial response, rendering the therapy ineffective ...

City St. George’s researchers identified 9 genetic signatures and epigenetic changes driving lapatinib resistance in HER2-positive breast cancer. Cancer scientists from City St George’s, University of ...

Current drugs for pancreatic cancer lose effectiveness within months because the tumor becomes resistant. Now, a group from ...

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Serial circulating tumor DNA analysis can demonstrate rapid clonal dynamics that evolve during response and resistance to both standard chemotherapy and targeted therapy of BRAF-mutant colon cancer ...

There’s nothing retro about retrons, which are bacterial molecules that produce DNA. Although retrons ordinarily serve an immune function in bacteria, they can, upon modification, acquire a genetic ...