The National Prion Disease Pathology Surveillance Center (NPDPSC) was established in 1997 at the Division of Neuropathology of Case Western Reserve University. Several European countries also have ...

The National Prion Disease Pathology Surveillance Center (NPDPSC) at Case Western Reserve University will receive up to $20 million in funding as part of a grant renewal from the Centers for Disease ...

A new study by SISSA and the University of Campania 'Luigi Vanvitelli' delves into the dynamics that cause prion proteins to take on the pathological form responsible for serious neurodegenerative ...

Two recent cases of prion disease in the U.S. may have been caused by contaminated deer meat, though the connection is still unproven. Reading time 3 minutes A new study might point to the first signs ...

Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein. Notably, C-transmembrane form of prion protein and ...

A substantial species barrier prevents chronic wasting disease (CWD), a cervid prion disease with unknown zoonotic potential, from being transmitted to humans, new NIH data suggested. Healthy human ...

Transmissible spongiform encephalopathies (TSEs), the diseases caused by proteinaceous infectious particles, or prions, comprise a group of fatal neurodegenerative diseases that take their name from ...

In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This ...

What are they? The prion protein (PrP) is a widely expressed, membrane-associated protein transcribed from the PRNP gene, which is highly conserved among mammals. PrPs exist in two forms: a common, ...

In a new study, researchers have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, they say, reveals the mechanism for how prions can jump ...