Oleanolic acid (OA) is a naturally occurring pentacyclic triterpenoid widely distributed in medicinal plants and fruits. It has garnered significant attention owing to its diverse pharmacological ...

More information: Giulio Mazzarotti et al, Oleanolic Acid Modulates DNA Damage Response to Camptothecin Increasing Cancer Cell Death, International Journal of Molecular Sciences (2024). DOI: 10. ...

STEP ONE: Soak them in a bowl (with stems on) in roughly one gallon of very cold water, and add 1/4 cup of white distilled ...

Oleanolic acid was extracted from grape pomace using nuclear magnetic resonance (NMR). It showed a significant effect on the viability of cancer cell lines when combined with Camptothecin, a ...

Oleanolic acid shows promise as an adjunct therapy for overcoming sorafenib resistance in HCC. By reducing cell aggressiveness and restoring drug sensitivity, OA may enhance the therapeutic ...

“Use of Oleanolic Acid may allow us to reduce the Camptothecin drug concentration needed to get the desired anti-cancer result,” says senior author Giordano. “Lower doses of chemotherapy suggests the ...

To this day, only oleanolic acid – produced in China – has been marketed. However, maslinic acid has gained importance as it is not still on the market and has a greater biological activity.

Oleanolic acid shows promise as an adjunct therapy for overcoming sorafenib resistance in HCC. By reducing cell aggressiveness and restoring drug sensitivity, OA may enhance the therapeutic ...

Oleanolic acid, oleanolic aldehyde, and 5-(hydroxymethyl)-2-furfural inhibited the growth of two species of oral bacteria: Streptococcus mutans, which causes cavities, ...

More information: Giulio Mazzarotti et al, Oleanolic Acid Modulates DNA Damage Response to Camptothecin Increasing Cancer Cell Death, International Journal of Molecular Sciences (2024). DOI: 10. ...