Please provide your email address to receive an email when new articles are posted on . Mirum Pharmaceuticals received first treatment approval for treatment of cerebrotendinous xanthomatosis. Ctexli ...

Lipid metabolism and storage mechanisms underpin essential cellular processes, ensuring energy homeostasis and membrane integrity. At the cellular level, lipids are synthesised and stored ...

Scientists have identified a protein that acts as a kind of traffic controller for fat inside cells, revealing a mechanism that could help explain how the body regulates energy storage and why things ...

Disruption of fatty acid storage triggers tumor cell death in preclinical models of high-risk medulloblastoma, offering a ...

The FDA on Friday approved chenodiol (Ctexli) for the treatment of cerebrotendinous xanthomatosis (CTX) in adults. Chenodiol -- a naturally occurring human bile acid also known as chenodeoxycholic ...

AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...

Researchers at the Salk Institute have used CRISPR to uncover hidden microproteins that control fat cell growth and lipid storage, identifying one confirmed target, Adipocyte-smORF-1183. This ...

Chanarin-Dorfman syndrome (CDS) is a rare, multisystemic, neutral lipid storage disease (NLSD) where the triglyceride accumulates in the leukocytes and other organs. Image Credit: ...

The Food and Drug Administration approved Mirum Pharmaceuticals' Ctexli to treat Cerebrotendinous Xanthoma, a very rare lipid-storage disease. The approval makes Ctexli, or chenodiol, the first ...

In a recent review published in Advances in Food and Nutrition Research, researchers assessed the function of lipids in metabolic diseases. Lipids play an essential role in the proper functioning of ...

Liver diseases are a growing global health and economic challenge. High alcohol consumption, aging, and increased exposure to metabolism-related risk factors may contribute to an increase in mortality ...