Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have deciphered a key mechanism ...

Developing effective immunotherapies for acute myeloid leukemia (AML) has long been hampered by a critical challenge: Therapy ...

New findings show that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment outcomes for pediatric patients with B-cell acute lymphoblastic leukemia (B ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

Acute myeloid leukemia (AML) is one of the most aggressive blood cancers and is characterized by the rapid growth of immature ...

In a new study presented at the American Association for Cancer Research (AACR) Annual Meeting and published in Blood Cancer Discovery, titled, “Single-cell Transcriptional Atlas of Human ...

Researchers have discovered 2 leukemia stem cell subtypes with distinct epigenetic and transcriptional signatures. “Our study sets the stage to unlock new insights into the mechanisms governing ...

Precursor B-cell acute lymphoblastic leukemia is a fast-growing leukemia that affects early B cells in bone marrow. It’s both more common and has a better outlook in children. Leukemia is a type of ...

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments in ...

As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ...