A research team led by City University of Hong Kong (CityUHK), in collaboration with the University of Zurich, has uncovered ...

The kidney plays a pivotal role in regulating calcium levels within the body. Approximately 98% of the filtered calcium is reabsorbed in the nephron, and this process is tightly controlled to maintain ...

Kidney organoids derived from human pluripotent stem cells (hPSCs) are now being used as models of renal disease and nephrotoxicity screening. However, the proximal tubules (PTs), which are ...

Urine formation happens inside your kidneys and is part of a carefully balanced system that keeps your body healthy by ...

Researchers found that probenecid slowed PKD progression. Their work revealed that it activates urate signaling, improving ...

The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly ...

The kidneys play a dominant role in regulating both the volume and composition of the extracellular fluid. They function to ensure that the body maintains a homeostatic internal environment. They ...

While investigating the underlying causes of a rare skin disorder, a researcher at Massachusetts General Hospital (MGH) discovered a previously unknown mechanism in the kidneys that is important for ...