Craniofacial development is a complex process that involves the specification of diverse and transient cell types. However, our understanding of these processes and the cell-types present during human ...

Translating genome-wide association study (GWAS) loci into causal variants and genes requires accurate cell-type-specific enhancer–gene maps from disease-relevant tissues. Building enhancer–gene maps ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

The Joint Open Genome and Omics Platform 1.0 (JoGo 1.0) catalogs 19,194 human genes with a novel naming system. Researchers expect the database to benefit medicine and genomics, and to provide a ...

Numerous genetic studies have identified many risk variants for type 2 diabetes (T2D)—but which genes and proteins are actually involved in the disease mechanisms? An international team led by ...

Late-onset Alzheimer's disease is a debilitating, progressive neurodegenerative disease that affects about 7 million Americans, a figure that is expected to nearly double by 2050, according to the ...

Routine genetic testing for maturity-onset diabetes of the young (MODY) could be cost-effective or even save money, depending on the price of the test and the prevalence of MODY in the population ...

The most common types of color blindness, or color vision deficiency, are genetic. However, other types may develop due to injuries, eye diseases, health problems, and side effects of treatment.