GPCRs are the largest receptor class, affecting almost every aspect of human physiology, with 35% of all approved drugs acting on GPCRs. They regulate sensory and neuronal signaling, as well as a ...
Researchers at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), led by Prof. Gracjan Michlewski, ...
Ajit Prakash is a postdoctoral researcher in biochemist Sharon Campbell’s group at the University of North Carolina at Chapel Hill. He studies G-protein signaling, protein dynamics, and biophysical ...
A small molecule modulates the oligomerization and condensation of the protein (left, untreated). Upon addition of the molecule (right), these condensates become more rigid, effectively blocking the ...
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