The colorful dots at the center are cytotoxic granules used to destroy infected or cancerous cells. Credit: F. Lemaitre @ ...

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

A collaboration between UNIGE and CHUV-UNIL has made it possible to visualise the mechanisms of cytotoxic T cells in three ...

Cryo-expansion microscopy has enabled researchers to visualise the three-dimensional organisation of cytotoxic T lymphocytes destroying cancer cells in their near-native state, revealing nanoscale ...

A collaboration between the University of Geneva and Lausanne University Hospital has shown in new detail how the body's defenses fight back against malignant cells. Those defenses involve T ...

Cancer immunotherapy has revolutionized treatment for many patients, but significant challenges remain in predicting who will respond to these life-saving treatments. A new comprehensive review ...

Study identifies citraconate as a metabolic regulator that reverses T cell exhaustion, suppresses lipid-driven toxicity and ...

Universal solid tumor therapy with CD5-deleted, DSG2-directed CAR-T cells. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.