Throughout our lives, our bones are continuously remodeled to maintain strength, repair injuries and adapt to new stresses. Bone dynamics depend on two associated cell types: osteoblasts, which are ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

For years, clinicians have noticed that people living with major depression often show unexpectedly fragile bones. What ...

Crohn’s, a form of inflammatory bowel disease (IBD), is associated with a higher risk of bone density loss and even osteoporosis. Find out why.

It’s common to think of your bones as solid and unchanging, but they’re composed of living tissue constantly in flux. Consider: Every year, 15% of your spine and 5% of your hips are replaced with new ...

In a new study, researchers from Japan reveal that iSN40 suppresses osteoclast differentiation and bone matrix resorption, offering a potential therapeutic approach for osteoporosis by restoring the ...

Explore the vital role of bone marrow stem cells. Learn how they drive bone remodeling, immunity, and skeletal health in this complete guide.

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan. Hypoxic conditions resulted ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...