The Warburg effect, or aerobic glycolysis, facilitates tumor cell growth. Pyruvate kinase M2 (PKM2) and PKM1 are glycolytic enzymes with overlapping but distinct roles in tumorigenesis that are only ...
Eukaryotic secretory proteins cross the endoplasmic reticulum (ER) membrane through a protein-conducting channel contained within the ribosome–Sec61translocon complex (RTC). Using a zinc-finger ...
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