Researchers applied a new technology to generate the full inventory of mutations in the bacterial species Escherichia coli where the antibiotic rifampicin attaches to and disables an essential ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

As more and more bacteria develop resistance to the drugs designed to kill them, a new study has found that even a relatively new antibiotic isn’t immune. Researchers have uncovered a gene ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

Researchers have combined the bacteria-killing actions of two classes of antibiotics into one, demonstrating that their new dual-action antibiotic could make bacterial resistance (almost) an ...

Antibiotic resistance is a major public health problem. Few new molecules are in development, but a new antibiotic called clovibactin brings hope. This drug, isolated from bacteria that haven't ...

The results of research led by scientists at Harvard Medical School suggest that a natural product antibiotic first isolated back in the 1940s may be effective against potentially lethal, multidrug ...

An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study published May 16 th in the open access journal PLOS Biology by James ...