The San Francisco 49ers didn’t list Yetur Gross-Matos on Thursday’s injury report, which was a good sign that the defensive lineman, who has been out since Week 15, would return in Week 15. Gross-Matos practiced on Friday and is expected to be activated from the Injured Reserve on Saturday.

It appears the illness that limited San Francisco 49ers running back Christian McCaffrey won't have any effect on his Week 15 availability. McCaffrey was not on the Friday injury report, an indicator that he's good to go for Sunday's game against the Tennessee Titans at Levi's Stadium.

The depth of the San Francisco 49ers, especially on defense, is insanely thin. They cannot afford to have a few players or more on that side of the ball out. U

San Francisco coach Kyle Shanahan explained how his defense plans to slow down Tennessee Titans QB Cam Ward during an interview on "49ers Game Plan."

The San Francisco 49ers have needed someone to step up on the edge, and luckily, one of their free-agent signings has worked out better than expected.

Now the 49ers are on the upswing and the Eagles look as if they’re lost again. They lead the NFC East, but have gone from 8-2 to 8-5, giving up 575 yards in the three losses. Hurts is spewing turnovers, and had two on one play (an interception and a lost fumble) on the same play in a 22-19 overtime loss to the Los Angeles Chargers.

The San Francisco 49ers have shared an injury update that could completely change the balance of power in the NFC.

The middle linebacker opted to sign with Dallas instead of San Francisco last season, but it's all worked out great for both parties.

San Francisco 49ers quarterback Brock Purdy has a 4–1 record as a starter this year, despite battling a turf toe injury he suffered at the very start of the season.